Mission District · San Francisco
Fire-Kissed Since Day One
Classic pies and calzones from the heart of San Francisco's Mission District - crafted with love on 21st Street.
Order OnlineOur Story on 21st Street
Serrano's Pizza has been a cornerstone of San Francisco's Mission District for years, serving up authentic Italian pies that keep the neighborhood coming back. We use quality ingredients and time-tested recipes to craft every pizza, calzone, and plate that leaves our kitchen. Whether you're grabbing a quick slice on the go or feeding the whole crew with an extra-large pie, we bring bold flavor and honest food to 21st Street - every single day.
3,364 Reviews
What We're Famous For
Straight From the Neighborhood
Excellent tasty spaghetti with meatballs and sausage. A hearty portion served with garlic bread. A great meal. Will definitely order again.
Serranos Pizzeria over 21st in the Mission never disappoints. The same pizza flavor I used to taste from back when I was younger and strolling around on a Friday or weekend night after hours. Their Slice Cheese pizza still like back in the day. Good quality ingredients denoted by its original flavors.
Good Questions
What meals do you serve?
Serrano's Pizza is a beloved Italian pizza restaurant in San Francisco serving classic, customizable pizzas for every occasion. We offer individual cheese slices, perfect for a quick lunch or casual dining. Our pizzas come in four sizes: Small (12"), Medium (14"), Large (16"), and X-Large (18"), each featuring a rich tomato sauce and melted cheese base. Every pizza can be personalized with your favorite toppings. Whether you're feeding a crowd or enjoying a solo slice, Serrano's Pizza has the perfect Italian meal for you.
Do you offer delivery or takeout?
Yes, we offer both delivery and pickup. Order your favorite pizza conveniently today!
Where are you located?
Serrano's Pizza is located at 3274 21st Street, San Francisco, CA 94110.
What areas do you serve?
Serrano's Pizza proudly serves the Mission District, Noe Valley, Castro, Potrero Hill, Bernal Heights, Glen Park, Dolores Heights, Inner Mission, 16th Street corridor, and surrounding San Francisco neighborhoods.
Find Us
Address
3274 21st Street
San Francisco, CA 94110
Phone
Ordering
Delivery & Pickup available
Hours
Monday11:00 AM - 11:00 PM
Tuesday11:00 AM - 11:00 PM
Wednesday11:00 AM - 11:00 PM
Thursday11:00 AM - 11:00 PM
Friday11:00 AM - 11:00 PM
Saturday11:00 AM - 11:00 PM
Sunday11:00 AM - 11:00 PM